Thanks for first considering our getting started page. Now let's get into some more details specific to Prusa 3D Printers.
To print with less risk of hang-ups, we swapped to a Bondtech heatbreak. This moves the PTFE junction farther up and away from the melt zone. Swapping to e3d v6, lite6, or revo, slice engineering, or hardware without features/junctions at the top of the edge of the melt zone can similarly reduce hang-ups.
Here's how one customer reworked his Minis for a reliable print farm fleet.
Like the Bambu AMS, the Prusa Mini uses an edge roll style spool holder. Hopefully our suggestions and solutions for the Bambu AMS can also help get a better unspooling experience on the Prusa Mini.
To avoid trade-offs and print with typical lower temperatures, we recommend swapping to e3d v6, lite6, or revo, slice engineering, or other hotends and heatbreaks without features/junctions at the top of the melt zone to reduce hang-ups.
Still, stock Prusas can perform well. Out of Darts operates a fleet of 10s of Prusa MK printers with stock heatbreaks and enjoys high reliability with Protopasta filaments.